Don uses Charlie and Megan's expertise when the FBI is called to the scene of a federal judge's wife's murder, on the second season premiere. Dylan Bruno stars as Colby Granger, a new Los Angeles FBI agent whose tour of duty with the Army's Criminal Investigation division allowed him the chance to see the world beyond Boise, Idaho where he grew up. When a judge's wife is shot and killed, Don and his team look into the judge's cases to determine if one of his verdicts led to the murder. Using the judge's past rulings and Megan's expertise in profiling, Charlie creates a mathematical theory to identify the two most probable suspects from the case files. However, when the team discovers a link between the 2 suspects, the investigation goes in an unexpected direction.

Don and his team must find who is responsible for kidnapping the family of a jewelry store owner before they are killed. A robbery at a jewelry store turns out to be a kidnapping when the store owner's wife and young daughter are abducted. But when Don and his team get deeper into the investigation, they discover that the heist may not have been a complete surprise to the owner. Meanwhile, Charlie and Amita have their first official date. They agree not to talk about work. Unfortunately, the date goes badly because they seem to have nothing else to discuss, leaving Charlie wondering what to do.

Don and his team search for the stalker of a pop princess which turns into a murder investigation of a paparazzo. When an alleged stalker breaks into a famous pop singera 's house, Don and his team are brought in to lead the investigation. Using the fan letters she received as evidence, Don turns to Charlie, who uses Forensic Information System for Handwriting and discovers that there are two senders a " one of them a copycat. The agents are thrown another curve when a celebrity photographer taking photos of the pop princessa ' house is murdered, and they learn that the pop princess may not be so innocent. Dr. Larry Fleinhardt acquires a 1931 Ford roadster, but is reluctant to drive it anywhere but on campus or to and from his nearby home.

Don and his team must solve the murder of a CFO of a large energy corporation who is found murdered on her doorstep and her young son is the only witness. Don and Megan are called to a murder scene when the CFO of a powerful energy company, who was about to testify against fellow executives for stock fraud, is found dead at home with the only witness being her 11-year-old son. Knowing there could be thousands of disgruntled ex-employees, Don calls on Charlie to help narrow down the list of potential suspects, but is surprised when the investigation takes them in a different direction.

Don and his team find a suspicious code during a raid which Charlie determines is part of a secret plan to assassinate a Colombian exile living in Los Angeles. Along with David Sinclair and new FBI Agent Colby Granger, Don discovers a secret code during a raid and enlists Charlie's help to crack it. Using an elaborate game theory model called hide and seek, Charlie discovers that it is a plan for the assassination of a Columbian exile living in Los Angeles. Charlie and Megan combine their expertise and work closely together to try to prevent the murder from taking place.

Don and his agents must uncover who interfered with a counter-terrorism exercise before deadly results occur. A week-long series of counter-terrorism exercises are put to the test by Homeland Security in Los Angeles, but when the first one is violated by someone who releases a potentially lethal gas in the subway system, Don and his team are called in to find the culprit. Further investigation leads them to an unlikely suspect trying to prove a point about the city's lack of preparedness.

in this episode: don and his team was called when a father is killed in a home robbery. A series of home invasions become increasingly violent. to solve the mystery Charlie applied a data-mining procedure to find a link between the robberies and uncovers a connection between the victims insurance and wireless companies which exposed a much larger operation.

A routine drug bust unveils a sensitive issue which Charlie takes to heart. Megan and a team of FBI agents bust a major methamphetamine lab, but lose the kingpin when he sets off a bomb and escapes, killing one of the agents under Megan's command. But when Charlie gets his hands on a computer hard drive left behind, he uncovers a disturbing photo and, against Don's wishes, pursues its origin.

When several people in Los Angeles suffer from seizures as a result of product tampering of over-the-counter medications, Don and his team discover that a former chemist from a large pharmaceutical company is to blame. While tracing the culprit to the Sibley mountains, the team meets up with Special Agent Edgerton (Lou Diamond Phillips), who is tracking a cattle rancher-turned-federal fugitive for selling tainted beef and killing a U.S. Marshall. Megan figures out that their meeting isn't random, as the two fugitives have something in common.

In the lab of the Heritage Museum , Jennifer Abernathy is working on some Native-American artifact. Once her work is done, she gathers her things and exits but doesn't make it outside as someone grabs her. Don and his team are brought to the scene to investigate who killed the woman and why. Alan has problems letting go of the past. Amita and Larry give Charlie advice on his father's problem.

Charlie helps Don and his team to find an arsonist who has set four fires so far with Molotov cocktails. Along with LAFD Arson Investigator Noah Stevens, the team will investigate the fire of an SUV that caused the death of a man.

When Don and his team are called to the murder scene of a Los Angeles gang member, they learn that it is a fellow agent who had been working undercover. Without exposing the agent's cover, Don must investigate his murder by a rival gang and try to crack the gangs' leadership and territories to find the suspect. But the agents are surprised when they learn who is responsible for the source of the rivalry.

A Russian 20-year-old man is killed after he played and won at Blackjack at a L.A. Card Club. There were four robberies reported at this club in the past six months. Don requires his brother's help when they find books with equations in the dead man's bag. Larry will find the equations a tad too familiar for his taste, which will lead him to helping Charlie and the FBI more than he usually does.

A teenager, from the same part of India where Amita is from, is discovered in the basement of an old downtown hotel. It is believed she was being tortured. It is discovered that the girl and three others were victims of black market organ-harvesting.

A DNA synthesizer that has the capability of customizing diseases, is stolen from the campus where Charlie teaches. Don fears the thieves may be terrorists out to start or advance a bio-warfare program. He also believes the theft was an inside job and the chief suspect is one of Larry's top students. Back at home, Charlie discovers that his late mother was once a gifted musician.

A bomb placed under a government car parked near a U.S. Army Recruitment Office explodes killing a man and leaving his wife in shock. Don and his team try to stop the bomb makers before more antiwar protests kill more civilians. Don has to contend with a retired FBI agent who investigated a similar bombing 35 years earlier. The retired agent insists the culprit is an activist that Alan Eppes knew in the 1960s who has been missing since. The retired agent's old school style clashes dramatically with the way Don runs his FBI team.

A psychic called a search team and tipped them off about a location in the middle of nowhere where a crime has been committed. When the search team arrives there, they find a crime scene. Don and his team are called in. Charlie and the psychic will collide as one is all about facts and science and the other is not.

While talking on her cellphone, a woman named Saida is taken and killed the day before she had an important interview. Saida was an Iraqi citizen in the states to make a documentary. She was an activist who received death threats. Don and his team work with Agent Kareem Allawi. Charlie has dinner with Susan Berry an old friend who is in town for a book signing. Both of them seem to have a liking for one another.

As Don and his team investigate the motive behind two students' deadly school shooting, Charlie uses the school's radio frequency identification system to track the shooters' movements through the school's hallways. But when Charlie notices an abnormal pattern, Don and his agents reevaluate the evidence and discover an unlikely third participant. Larry asks Megan to dinner at an Ethiopian restaurant for their first date.

When an ATF agent is found dead amid questionable circumstances, Don demands to take on the case, which revolves around an elaborate bank heist, after he learns the victim is his ex-girlfriend. As the pressure of his job mounts, Don recognizes the impact his professional life has on his personal life and he decides to investigate his flirtation with AUSA Robin Brooks.

After an unknown man opens fire in the FBI offices, Don and his team must investigate his motive and his connection to a dangerous arms dealer who is on trial. After almost getting shot, Charlie is visibly shaken and reluctant to return to the offices, hindering his contribution in the case.

An FBI investigation into a computer hacking scam, which taps into a bank's system to gain access to customer's identities and financial assets, becomes personal for Don when the Russian mob spearheading it comes after him and threatens the safety of Charlie and Alan.

Don enlists Charlie's help when the bodies of five young Asian girls found washed up are suspected of being infected with the Avian influenza virus. To prevent the potential spread of the Avian flu, Don puts a rush on the investigation, which takes a surprising turn when David and Colby discover a clue on one of the girls' bodies. Meanwhile, Amita considers a move to Harvard University, which causes Charlie to re-evaluate his feelings for her.

episode 24.When two women are found dead with an apparent drug overdose, Don suspects a serial killer. Charlie's help on Don's case is hindered by his bizarre dream about his mother.The details surrounding a young womans death suggests to Don and his team that she could have been murdered by a serial killer..